What Is Hexahydrocannabinol Craze

That claim that Hexahydrocannabinol is naturally occurring in cannabis isn’t confirmed by peer-reviewed research. The cannabinoid craze continues, with a new chemical called hexahydrocannabinol (H.H.C.) hitting the scene. An interesting thing about this chemical is that while there seems to be quite a lot of excitement around it and people have many questions, and it’s not exactly new. Roger Adams chemist, first discovered the semi-synthetic compound in the 1940s by hydrogenating delta-9 T.H.C., a primary psychoactive compound found in cannabis. Adams added two hydrogen molecules to delta-9 T.H.C., converting T.H.C. to H.H.C.

What Is Hexahydrocannabinol Craze

Hydrogenated cannabidiol (H.H.C.) is the result of adding hydrogen atoms to the cannabinoid delta-9 tetrahydrocannabinol (T.H.C.) to create a non-psychoactive molecule. It has no psychotropic effects and is therefore not considered a controlled substance.A molecule is said to be hydrogenated if it has had hydrogen atoms added to it. This process is also known as hydrogenation. This process can be carried out using various methods such as chemical synthesis or a catalyst in a reaction between an organic compound and hydrogen gas.

In the case of H.H.C., it is created by adding hydrogen atoms to delta-9 T.H.C., creating delta-8 tetrahydrocannabinol (T.H.C.) and delta-9 tetrahydrocannabinol propionate (THCP). H.H.C. is then removed from the THCP by vacuum distillation and purified through crystallization or recrystallization.

According to Roger Brown, the president and founder of A.C.S. Laboratory, cannabis, hemp, and CBD testing laboratory in Florida, H.H.C. can be produced from either hemp or cannabis plants. He claims that hemp plants contain higher THCV and CBDV than cannabis plants, making them more suitable for creating H.H.C.

Converting cannabinoids into H.H.C. is called hydrogenation and is carried out at high temperatures and pressures within a vacuum furnace under an inert gas atmosphere. The process requires high purity gases such as argon or nitrogen. Some impurities can cause side reactions that result in lower yields or different products. Still, science can also convert it from hemp-derived cannabinoids such as delta-8. According to Roger Brown, the president and founder of A.C.S. Laboratory, a cannabis and CBD testing laboratory in Florida.

The Hemp and Cannabis Council (H.C.C.) is a non-profit industry trade association that promotes the use of hemp and cannabis in the United States. They have a page on their website dedicated to the benefits of hemp-derived CBD. They say it can be further processed in a lab using a chemical reaction called hydrogenation. An article on their website says that hydrogenation can be used to make margarine, which is a common substitute for butter.

However, it’s important to note that hydrogenation is also used to process other dangerous chemicals like polyethylene, which makes plastic bags and containers, says Allison Justice, Ph.D., C.E.O. of The Hemp Mine, a vertically integrated hemp CBD business in South Carolina. Some of these chemicals are hazardous to human health and the environment and cause serious harm.

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Is H.H.C. Legal?

The legal status of H.H.C. is currently ambiguous. Some say it’s legal if manufactured from a hemp-derived compound like delta-8, while others disagree. The original Controlled Substances Act of 1970 states that hemp fiber is not illegal. However, once you start doing chemical extractions on it, it is. Delta-8 is an isomer of delta-9 T.H.C. 

A 1986 congressional act called the Federal Analogue Act states that if you make a molecule related to something that’s a Schedule I controlled substance, what you made can be considered Schedule I and illegal. So, the sale of these unregulated products, which could expose consumers to potential toxicities, should not be allowed.

The first part of the paragraph is too convoluted and needs to be broken into separate sentences. It’s also confusing that the author is talking about two different things at the same time — federal laws and scientific consensus. The latter part of the paragraph also contains many unnecessary words and doesn’t flow naturally.

I would suggest starting with: “The legal status of H.H.C. is currently ambiguous, with some saying it’s legal if manufactured from a hemp-derived compound like delta-8, while others disagree.” Then I would remove everything after “However.” This section is just repeating what was already said in the previous sentence — that the legality of H.H.C. still isn’t clear. The last sentence doesn’t flow naturally as part of this paragraph; it feels like it belongs in a different section.

In the original Controlled Substances Act of 1970, hemp fiber isn’t illegal. However, once you start doing chemical extractions on it, it is.”We should legalize cannabis and regulate the market,” Russo stated. Unlike Russo, others argue that it’s federally legal because it’s a hemp derivative and therefore covered under the 2018 Farm Bill.

Nolan Jackson, an attorney at Frost Brown Todd who advises clients nationwide regarding hemp laws and regulations at the state and federal levels, and regulatory counsel to the U.S. Hemp Roundtable, see both sides of the legal argument. “The argument is that the 2018 Farm Bill defines ‘hemp’ to include all parts of the plant with a delta-9 T.H.C. concentration of 0.3% T.H.C. or more minor on a dry-weight basis. 

hemp

Removes hemp from scheduling under the federal Controlled Substances Act and protects hemp and hemp products in interstate commerce,” Jackson stated in an email. “Because H.H.C. is naturally occurring in the hemp plant, it constitutes ‘hemp’ under the 2018 Farm Bill. It is not a federally controlled substance and is protected in interstate commerce.” “There are two sides to this argument,” Nolan Jackson, an attorney at Frost Brown Todd. Who advises clients nationwide regarding hemp laws and regulations at the state and federal levels, said in an email. 

“One side argues that H.H.C. is federally legal because it’s a hemp derivative covered under the 2018 Farm Bill. The other side argues that H.H.C. is federally illegal because it contains more than 0.3 percent T.H.C. on a dry-weight basis.” “In my opinion, H.H.C. is federally legal because it’s a hemp derivative and covered under the 2018 Farm Bill,” Nolan said. “It is not a federally controlled substance and is protected in interstate commerce.”

The legal status of hemp is a confusing topic, but I think I’ve figured it out. Hemp is federally legal because it has a low concentration of T.H.C., the active ingredient in marijuana.  As an attorney at Frost Brown Todd, who advises clients nationwide on hemp laws and regulations at the state and federal levels, and regulatory counsel to the U.S. Hemp Roundtable, I can see both sides.

I’m not sure if you’re aware, but I’ve been working as a PM for six months. It’s been a great experience so far, and I can tell that my skills are improving every day. I’m enjoying the work, and my team seems to like me. But there are still times when I feel like I’m struggling to keep up with everyone else on my team. They seem to have such a solid grasp of all the different parts of their job that they intuitively know what needs to be done and how to do it.

I don’t know where they learned all this stuff or how they got so good at it so quickly. Still, I know that I need to figure out how to do a better job of mastering everything on my own plate as soon as possible if I want to keep up with them. What amazes me most about them is how quickly they can turn around a new feature or fix a bug. They seem to be able to do it in their sleep. Some days, I might spend hours trying to figure something out before giving up and asking for help from one of them. They look at whatever problem we’re trying to solve for five minutes. Then they magically come up with an elegant solution that doesn’t just work but also makes sense. It makes me wonder what their secret is. How did they get so good at this?

hemp

Brown describes the effects of high-happy cannabinoids as “a feeling of happiness, increased energy, and low level of euphoria.” He states he doesn’t think H.H.C. is as effective as cannabis (predominantly delta-9 T.H.C.) in terms of effects or medicinal benefits. As far as potency, H.H.C. is less potent than delta-9 and potentially less potent than delta-8; however, that varies “because the chemistry that creates H.H.C. is inconsistent across all methods.”

“The way H.H.C. binds to the endocannabinoid receptors is different from T.H.C. and similar to delta-8,” Brown communicated in an email. “It’s not about more or less potent, and it’s different—both the effects and different potency measures.” Here’s what I think: H.H.C. isn’t a cannabinoid. It’s psychedelic.

H.H.C. is different from T.H.C. and similar to delta-8. But it’s not about more or less potent; it’s different — both the effects and various potency measures. I think he means delta-8 has more of a psychedelic effect than delta-9. Delta-8 doesn’t bind as well to endocannabinoid receptors as delta-9 does.

Brown says that A.C.S. Laboratory tests for H.H.C. every day, most commonly in edibles or vaporizers. Brown started receiving an “incredible” number of inquiries about H.H.C. testing around October of last year, prompting the lab to research and develop a proper testing method for the cannabinoid. The tests for H.H.C. products are entirely different from delta-9 or delta-8. However, the goal for testing these products is the same: to ensure it is safe for consumption and doesn’t contain any residual metals, solvents, pesticides, etc.

As a product manager, I have worked on a few projects at my current company. A couple of them are in the early stage, and a few are in the later stage. As part of my job, I am expected to know the product, the market, and the competitor landscape. A few months back, I was asked to give an update on one of our products in its early stage, i.e., not yet launched to market. Due to some internal issues, we could not launch that product as expected, and now we are thinking about how do we make it successful.

The feedback I received from my manager was something like this. This is too high a level. We need to know more details. 

What is the pain point you are solving with this product? 

Who are your competitors?

 What is your go-to-market strategy? 

How many people are using this product? 

What is their profile? 

How much money do they make? 

How many people will use this product?

That was when I realized that I should have done my homework before giving that update, and I should have prepared a deck for it to answer all those questions quickly. So I started learning how to create a PowerPoint presentation online and then began creating decks for each of our products and soon started using them as part of my regular work routine.

The testing process, according to Brown: “It’s really starting to move in the marketplace,” he says. “We test for it every single day from a potency level and also from other minor cannabinoids that are along with it, and also for the metals from the safety perspective,” he declares. Now, this could be a bit confusing. What does “H.H.C.” mean? Is it a cannabis product? Is it something else entirely? The answer is yes, H.H.C. is a cannabis product, but it’s not just any cannabis product. H.H.C. stands for “hemp-derived cannabinoid” or “hemp-derived cannabidiol.” But what exactly is hemp?

According to the U.S. Department of Agriculture (USDA), hemp is “the plant Cannabis sativa L., whether growing or not, the seeds of that plant, and every compound, manufacture, salt, derivative, mixture or preparation of that plant or its seeds.”  Hemp is often confused with marijuana (Cannabis sativa L.) which is defined as “all parts of the plant Cannabis sativa L., growing or not; the seeds thereof; the resin extracted from any part of such plant; and every compound, manufacture, salt, derivative, mixture, or preparation of such plant, its seeds or resin” (21 U.S.C. § 802(16)). 

So now we know that H.H.C. is a cannabis-based product containing cannabidiol (CBD). The Food and Drug Administration (F.D.A.) has yet to approve any CBD products for medical use in humans. However, the F.D.A. has approved at least one CBD product for use in animal health: Epidiolex® (cannabidiol oral solution). This product contains 99% cannabidiol and less than 1% tetrahydrocannabinol (T.H.C.).

Thanks for being part of the community!

Kevin

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